Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain:

Ligands
Code Name Link
NK Salicylaldehyde
DHT 5-alpha-dihydrotestosterone
SO4 Sulfate ion
Code : 2PIR
Header : HORMONE RECEPTOR
Title : Androgen receptor LBD with small molecule
Release Data : 2007-09-25
Compound :
mol_id molecule chains synonym
1 Androgen receptor A Dihydrotestosterone receptor
fragment: Ligand-binding domain (residues 669-919)
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
gene: AR, DHTR, NR3C4
Authors : Estebanez-Perpina, E., Arnold, A.A., Baxter, J.D., Webb, P., Guy, R.K., Fletterick, K.R.
Keywords : androgen receptor coactivator binding inhibitors AF-2 pocket, HORMONE RECEPTOR
Exp. method : X-RAY DIFFRACTION ( 2.1 Å )
Citation :

A surface on the androgen receptor that allosterically regulates coactivator binding.

Estebanez-Perpina, E.,Arnold, L.A.,Arnold, A.A.  et al.
(2007)  Proc.Natl.Acad.Sci.Usa  104 : 16074 - 16079

PubMed: 17911242
DOI: 10.1073/pnas.0708036104

Chain : A
UniProt : P10275 (ANDR_HUMAN)
Reaction : -