PDB ID: 2PEV
Hetero Atom Contents
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Code | Name | Style | Show | Link | |
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CIT | Citric acid | PoSSuM | |||
CL | Chloride ion | PoSSuM | |||
FID | (2s,4s)-2-aminoformyl-6-fluoro-spiro[chroman-4,4'-imidazolidine]-2',5'-dione | PoSSuM | |||
LDT | Idd594 | PoSSuM | |||
NDP | Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate | PoSSuM |
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Download interaction data: 2PEV
Structure summary
Code : | 2PEV PDBj RCSB PDB PDBe | ||||||||||||
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Header : | OXIDOREDUCTASE | ||||||||||||
Title : | Complex of Aldose Reductase with NADP+ and simaltaneously bound competetive inhibitors Fidarestat and IDD594. Concentration of Fidarestat in soaking solution exceeds concentration of IDD594. | ||||||||||||
Release Data : | 2007-04-17 | ||||||||||||
Compound : |
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Authors : | Petrova, T., Hazemann, I., Cousido, A., Mitschler, A., Ginell, S., Joachimiak, A., Podjarny, A. | ||||||||||||
Keywords : | OXIDOREDUCTASE, NADP, IDD594, FIDARESTAT | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 0.90 Å ) | ||||||||||||
Citation : |
Crystal packing modifies ligand binding affinity: The case of aldose reductase.
Cousido-Siah, A.,Petrova, T.,Hazemann, I.
et al.
PubMed: 22752989 |
Reaction
Chain : | A | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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UniProt : | P15121 (ALDR_HUMAN) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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