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Ligands
Code Name Style Show Link
CYT 6-aminopyrimidin-2(1h)-one
Non-standard Residues
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MSE Selenomethionine
Glycosylation
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Code : 2P2R   PDBj   RCSB PDB   PDBe
Header : RNA AND DNA BINDING PROTEIN/DNA
Title : Crystal structure of the third KH domain of human Poly(C)-Binding Protein-2 in complex with C-rich strand of human telomeric DNA
Release Data : 2007-06-12
Compound :
mol_id molecule chains synonym
1 C-rich strand of human telomeric DNA B Alpha-CP2, hnRNP-E2
fragment: third KH domain of human Poly(C)-binding Protein 2
mol_id molecule chains
2 Poly(rC)-binding protein 2 A
Source :
mol_id organism_scientific
1
synthetic: yes
other_details: this sequence in present in human telomeric DNA
mol_id organism_scientific organism_common expression_system
2 Homo sapiens  (taxid:9606) Human Escherichia coli BL21(DE3)  (taxid:469008)
gene: PCBP2
expression_system_strain: bl21(DE3)
expression_system_vector_type: plasmid
expression_system_plasmid: pet24a
Authors : James, T.L., Stroud, R.M., Du, Z., Fenn, S., Tjhen, R., Lee, J.K.
Keywords : PROTEIN-DNA COMPLEX, RNA AND DNA BINDING PROTEIN-DNA COMPLEX
Exp. method : X-RAY DIFFRACTION ( 1.60 Å )
Citation :

Crystal structure of the third KH domain of human poly(C)-binding protein-2 in complex with a C-rich strand of human telomeric DNA at 1.6 A resolution.

Fenn, S.,Du, Z.,Lee, J.K.  et al.
(2007)  Nucleic Acids Res.  35 : 2651 - 2660

PubMed: 17426136
DOI: 10.1093/nar/gkm139

Chain : A
UniProt : Q15366 (PCBP2_HUMAN)
Reaction : -