Het-PDB Navi2 (PDB: 2OUZ)

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Ligands
Code	Name		Style	Show	Link
C3D	(5r,6s)-6-phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-5,6,7,8-tetrahydronaphthalen-2-ol				PoSSuM

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Download interaction data: 2OUZ

Code :

2OUZ PDBj RCSB PDB PDBe

Header :

HORMONE/GROWTH FACTOR

Title :

Crystal Structure of Estrogen Receptor alpha-lasofoxifene complex

Release Data :

2007-05-08

Compound :

mol_id	molecule	chains	synonym
1	Estrogen receptor	A	ER, Estradiol receptor, ER-alpha
	fragment: Ligand Binding Domain, residues 306-551

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:562)
	gene: ESR1, ESR, NR3A1

Authors :

Vajdos, F.F., Pandit, J.

Keywords :

Nuclear receptor, SERM, estrogen, HORMONE-GROWTH FACTOR COMPLEX

Exp. method :

X-RAY DIFFRACTION ( 2.000 Å )

Citation :

The 2.0 A crystal structure of the ER{alpha} ligand-binding domain complexed with lasofoxifene

Vajdos, F.F.,Hoth, L.R.,Geoghegan, K.F. et al.
(2007) Protein Sci. 16 : 897 - 905

PDB ID: 2OUZ