Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
PEG Di(hydroxyethyl)ether
PGE Triethylene glycol
SO4 Sulfate ion
Modified Residues
Code Name Link
CS1 S-(2-anilinyl-sulfanyl)-cysteine
Code : 2OMA
Header : ISOMERASE
Title : Crystallographic analysis of a chemically modified triosephosphate isomerase from Trypanosoma cruzi with dithiobenzylamine (DTBA)
Release Data : 2007-11-20
Compound :
mol_id molecule chains synonym
1 Triosephosphate isomerase A,B TIM, Triose- phosphate isomerase
ec: 5.3.1.1
Source :
mol_id organism_scientific expression_system
1 Trypanosoma cruzi  (taxid:5693) Escherichia coli  (taxid:562)
strain: MEXICAN NINOA STRAIN
expression_system_strain: BL23(DE3)
expression_system_vector_type: PLASMID
expression_system_plasmid: PET23A
Authors : Rodriguez-Romero, A., Gomez-Puyou, A.
Keywords : Triosephosphate isomerase, Trypanosoma cruzi, protein interfaces, dithiobisbenzylamine, ISOMERASE
Exp. method : X-RAY DIFFRACTION ( 2.15 Å )
Citation :

Perturbation of the Dimer Interface of Triosephosphate Isomerase and its Effect on Trypanosoma cruzi.

Olivares-Illana, V.,Rodriguez-Romero, A.,Becker, I.  et al.
(2007)  PLoS Negl Trop Dis  1 : e1 - e1

PubMed: 17989778
DOI: 10.1371/journal.pntd.0000001

Inactivation of triosephosphate isomerase from trypanosoma cruzi by an agent AN AGENT THAT PERTURBS ITS DIMER INTERFACE.

Tellez-Valencia, A.,Olivares-Illana, V.,Hernandez-Santoyo, A.  et al.
(2004)  J.Mol.Biol.  341 : 1355 - 1365

PubMed: 15321726
DOI: 10.1016/j.jmb.2004.06.056

Chain : A, B
UniProt : P52270 (TPIS_TRYCR)
Reaction : D-glyceraldehyde 3-phosphate = glycerone phosphate.