PDB ID: 2OF4
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Structure summary
Code : | 2OF4 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSFERASE | ||||||||||||
Title : | crystal structure of furanopyrimidine 1 bound to lck | ||||||||||||
Release Data : | 2007-02-27 | ||||||||||||
Compound : |
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Source : |
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Authors : | Martin, M.W. | ||||||||||||
Keywords : | lck, kinase domain, TRANSFERASE | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.7 Å ) | ||||||||||||
Citation : |
Discovery of novel 2,3-diarylfuro[2,3-b]pyridin-4-amines as potent and selective inhibitors of Lck: Synthesis, SAR, and pharmacokinetic properties.
Martin, M.W.,Newcomb, J.,Nunes, J.J.
et al.
PubMed: 17276681 |
Reaction
Chain : | A | ||||||||
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UniProt : | P06239 (LCK_HUMAN) | ||||||||
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