Brand  (β version)

PDB ID: 2LFO

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Ligands
Code Name Style Show Link
CHO Glycochenodeoxycholic acid PoSSuM
GCH Glycocholic acid PoSSuM
Non-standard Residues
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Glycosylation
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Modification
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Structure summary

Code : 2LFO   PDBj   RCSB PDB   PDBe
Header : LIPID BINDING PROTEIN
Title : NMR structure of Cl-BABP/SS complexed with glycochenodeoxycholic and glycocholic acids
Release Data : 2012-07-11
Compound :
mol_id molecule chains synonym
1 Fatty acid-binding protein, liver A Fatty acid-binding protein 1, Liver basic FABP, LB-FABP, Liver bile acid-binding protein, L-BABP, Liver-type fatty acid-binding protein, L-FABP
Source :
mol_id organism_scientific organism_common expression_system
1 Gallus gallus  (taxid:9031) Bantam,chickens Escherichia coli  (taxid:562)
gene: FABP1
expression_system_vector: PET24D
Authors : Tomaselli, S., Cogliati, C., Pagano, K., Zetta, L., Zanzoni, S., Assfalg, M., Molinari, H., Ragona, L.
Keywords : heterotypic complex, bile acid binding protein, liver, bile acids, lipid binding protein, disulphide bridge
Exp. method : SOLUTION NMR
Citation :

A disulfide bridge allows for site-selective binding in liver bile acid binding protein thereby stabilising the orientation of key amino acid side chains.

Tomaselli, S.,Assfalg, M.,Pagano, K.  et al.
(2012)  Chemistry  18 : 2857 - 2866

PubMed: 22298334
DOI: 10.1002/chem.201102203

Reaction

Chain : A
UniProt : P80226 (FABPL_CHICK)
Reaction : -