Code : |
2KI6
PDBj
RCSB PDB
PDBe
|
Title : |
The FGF1-S100A13-C2A hetero-hexameric complex structure: A component in the non-classical pathway for FGF1 secretion |
Release Data : |
2010-03-09 |
Compound : |
mol_id |
molecule |
chains |
synonym
|
1 |
Synaptotagmin-1
|
A,F
|
Synaptotagmin I, SytI, p65
|
|
fragment: C2A domain
|
mol_id |
molecule |
chains |
synonym
|
2 |
Heparin-binding growth factor 1
|
B,E
|
HBGF-1, Acidic fibroblast growth factor, aFGF, Beta-endothelial cell growth factor, ECGF-beta
|
mol_id |
molecule |
chains |
synonym
|
3 |
Protein S100-A13
|
C
|
S100 calcium-binding protein A13
|
mol_id |
molecule |
chains |
synonym
|
4 |
Protein S100-A13
|
D
|
S100 calcium-binding protein A13
|
|
Source : |
mol_id |
organism_scientific |
organism_common
|
expression_system
|
1 |
Homo sapiens
(taxid:9606)
|
Human
|
Escherichia coli BL21(DE3)
(taxid:469008)
|
|
gene: SYT1, SVP65, SYT
expression_system_strain: BL21(DE3)
expression_system_vector: pET(20)
other_details: purified from heparin affinity column
|
mol_id |
organism_scientific |
organism_common
|
expression_system
|
2 |
Homo sapiens
(taxid:9606)
|
Human
|
Escherichia coli BL21(DE3)
(taxid:469008)
|
|
gene: FGF1, FGFA
expression_system_strain: BL21(DE3)
expression_system_vector: pGEX
other_details: purified from GST column
|
mol_id |
organism_scientific |
organism_common
|
expression_system
|
3 |
Homo sapiens
(taxid:9606)
|
Human
|
Escherichia coli BL21(DE3)
(taxid:469008)
|
|
gene: S100A13
expression_system_strain: BL21(DE3)
expression_system_vector: pGEX
other_details: purified from GST column
|
mol_id |
organism_scientific |
organism_common
|
expression_system
|
4 |
Homo sapiens
(taxid:9606)
|
Human
|
Escherichia coli BL21(DE3)
(taxid:469008)
|
|
gene: S100A13
expression_system_strain: BL21(DE3)
expression_system_vector: pGEX
other_details: purified from GST column
|
|
Authors : |
Krishna, S.M., Rani, S.G., Yu, C. |
Keywords : |
FGF1-S100A13-C2A hetero-hexameric complex, FGF1, S100A13, C2A, Calcium, Cell junction, Cytoplasmic vesicle, Glycoprotein, Lipoprotein, Membrane, Metal-binding, Palmitate, Phosphoprotein, Synapse, Transmembrane, Acetylation, Alternative splicing, Angiogenesis, Developmental protein, Differentiation, Growth factor, Heparin-binding, Mitogen, Polymorphism, PROTEIN TRANSPORT |
Exp. method : |
SOLUTION NMR |
Citation : |
The heterohexameric complex structure, a component in the non-classical pathway for fibroblast growth factor 1 (FGF1) secretion.
Mohan, S.K.,Rani, S.G.,Yu, C.
(2010)
J.Biol.Chem.
285
: 15464
- 15475
PubMed: 20220137
DOI: 10.1074/jbc.M109.066357
|