Brand  (β version)

PDB ID: 2KI4

Hetero Atom Contents

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Ligands
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Non-standard Residues
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DLY D-lysine
Glycosylation
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Structure summary

Code : 2KI4   PDBj   RCSB PDB   PDBe
Header : PROTEIN TRANSPORT
Title : FGF1-S100A13 complex structure: key component in non-classical path way of FGF1
Release Data : 2010-03-09
Compound :
mol_id molecule chains synonym
1 Heparin-binding growth factor 1 A,D HBGF-1, Acidic fibroblast growth factor, aFGF, Beta-endothelial cell growth factor, ECGF-beta
mol_id molecule chains synonym
2 Protein S100-A13 B S100 calcium-binding protein A13
mol_id molecule chains synonym
3 Protein S100-A13 C S100 calcium-binding protein A13
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli BL21(DE3)  (taxid:469008)
gene: FGF1, FGFA
expression_system_strain: BL21(DE)3
expression_system_vector: pET(20)
mol_id organism_scientific organism_common expression_system
2 Homo sapiens  (taxid:9606) Human Escherichia coli BL21(DE3)  (taxid:469008)
gene: S100A13
expression_system_strain: BL21(DE)3
expression_system_vector: pGEX
mol_id organism_scientific organism_common expression_system
3 Homo sapiens  (taxid:9606) Human Escherichia coli BL21(DE3)  (taxid:469008)
gene: S100A13
expression_system_strain: BL21(DE)3
expression_system_vector: pGEX
Authors : Krishna, S.M., Rani, S.G., Yu, C.
Keywords : acidic fibroblast growth factor, S100A13, tetrameric complex, Acetylation, Alternative splicing, Angiogenesis, Developmental protein, Differentiation, Growth factor, Heparin-binding, Mitogen, Polymorphism, Calcium, PROTEIN TRANSPORT
Exp. method : SOLUTION NMR
Citation :

The heterohexameric complex structure, a component in the non-classical pathway for fibroblast growth factor 1 (FGF1) secretion.

Mohan, S.K.,Rani, S.G.,Yu, C.
(2010)  J.Biol.Chem.  285 : 15464 - 15475

PubMed: 20220137
DOI: 10.1074/jbc.M109.066357

Reaction

Chain : A, D
UniProt : P05230 (FGF1_HUMAN)
Reaction : -
Chain : C
UniProt : Q99584 (S10AD_HUMAN)
Reaction : -