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Ligands
Code Name Style Show Link
Non-standard Residues
Code Name Show
CTG (5r,6s)-5,6-dihydro-5,6-dihydroxythymidine-5'-monophosphate
Glycosylation
Code Name Emphasize
Modification
Code Name Show
Code : 2KH7   PDBj   RCSB PDB   PDBe
Header : DNA
Title : Solution Structure of cis-5R,6S-thymine glycol opposite complementary guanine in duplex DNA
Release Data : 2009-12-01
Compound :
mol_id molecule chains
1 5'-D(*GP*TP*GP*CP*GP*(CTG)P*GP*TP*TP*TP*GP*T)-3' A
mol_id molecule chains
2 5'-D(*AP*CP*AP*AP*AP*CP*GP*CP*GP*CP*AP*C)-3' B
Source :
mol_id organism_scientific
1
synthetic: yes
mol_id organism_scientific
2
synthetic: yes
Authors : Brown, K.L.
Keywords : Thymine Glycol, DNA
Exp. method : SOLUTION NMR
Citation :

The cis-(5R,6S)-thymine glycol lesion occupies the wobble position when mismatched with deoxyguanosine in DNA

Brown, K.L.,Basu, A.K.,Stone, M.P.
(2009)  Biochemistry  48 : 9722 - 9733

PubMed: 19772348
DOI: 10.1021/bi900695e