Het-PDB Navi2 (PDB: 2JQ7)

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Ligands
Code	Name		Style	Show	Link

Non-standard Residues
Code	Name	Show
BB9	(2z)-2-amino-3-sulfanylprop-2-enoic acid
DBU	(2z)-2-aminobut-2-enoic acid
DCY	D-cysteine
DHA	2-amino-acrylic acid
MH6	3-hydroxy-2-iminopropanoic acid
TS9	(2s,3s,4r)-2-amino-3,4-dihydroxy-3-methylpentanoic acid

Glycosylation
Code	Name	Emphasize

Modification
Code	Name	Show
NH2	Amino group
QUA	8-hydroxy-4-(1-hydroxyethyl)quinoline-2-carboxylic acid

Download interaction data: 2JQ7

Code :

2JQ7 PDBj RCSB PDB PDBe

Header :

RIBOSOME/ANTIBIOTIC

Title :

Model for thiostrepton binding to the ribosomal L11-RNA

Release Data :

2007-07-03

Compound :

mol_id	molecule	chains
1	50S RIBOSOMAL PROTEIN L11	A

mol_id	molecule	chains
2	RIBOSOMAL RNA	B
	fragment: L11 BINDING DOMAIN, RESIDUES 1051-1108

mol_id	molecule	chains
3	THIOSTREPTON	C

Source :

mol_id	organism_scientific	expression_system
1	THERMOTOGA MARITIMA (taxid:2336)	ESCHERICHIA COLI BL21 (taxid:511693)
	gene: RPLK expression_system_strain: BL21 expression_system_vector_type: PLASMID expression_system_plasmid: PET11A

mol_id	organism_scientific
2	Escherichia coli (taxid:562)
	synthetic: yes other_details: IN VITRO TRANSCRIBED RNA CONSTRUCT.

mol_id	organism_scientific
3	STREPTOMYCES AZUREUS (taxid:146537)

Authors :

Jonker, H.R.A., Ilin, S., Grimm, S.K., Woehnert, J., Schwalbe, H.

Keywords :

RIBOSOME-ANTIBIOTIC COMPLEX, THIOPEPTIDE, ANTIBACTERIAL, THIAZOLE, THIAZOLINE, OXAZOLE, RIBOSOME, L11, TRANSLATION INHIBITION

Exp. method :

SOLUTION NMR

Citation :

L11 Domain Rearrangement Upon Binding to RNA and Thiostrepton Studied by NMR Spectroscopy

Jonker, H.R.A.,Ilin, S.,Grimm, S.K. et al.
(2007) Nucleic Acids Res. 35 : 441

PDB ID: 2JQ7