Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
CA Calcium ion
CTS Castanospermine
EDO 1,2-ethanediol
Code : 2JKP
Header : HYDROLASE
Title : Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with castanospermine
Release Data : 2008-09-30
Compound :
mol_id molecule chains synonym
1 ALPHA-GLUCOSIDASE (ALPHA-GLUCOSIDASE SUSB) A,B ALPHA-GLUCOSIDASE
ec: 3.2.1.20
fragment: RESIDUES 22-738
Source :
mol_id organism_scientific expression_system
1 BACTEROIDES THETAIOTAOMICRON  (taxid:226186) ESCHERICHIA COLI  (taxid:511693)
strain: VPI-5482
expression_system_strain: BL21
Authors : Gloster, T.M., Turkenburg, J.P., Potts, J.R., Henrissat, B., Davies, G.J.
Keywords : HYDROLASE, FAMILY 97, CASTANOSPERMINE, ALPHA-GLUCOSIDASE, GLYCOSIDE HYDROLASE, BACTEROIDES THETAIOTAOMICRON
Exp. method : X-RAY DIFFRACTION ( 1.99 Å )
Citation :

Divergence of Catalytic Mechanism within a Glycosidase Family Provides Insight Into Evolution of Carbohydrate Metabolism by Human Gut Flora.

Gloster, T.M.,Turkenburg, J.P.,Potts, J.R.  et al.
(2008)  Chem.Biol.  15 : 1058

PubMed: 18848471
DOI: 10.1016/J.CHEMBIOL.2008.09.005

Chain : A, B
UniProt : P71094 (SUSB_BACTN)
Reaction : Hydrolysis of terminal (1->4)-linked alpha-D- glucose residues successively from non-reducing ends of the chains with release of beta-D-glucose.