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Ligands
Code Name Style Show Link
J01 (2r,3z,5r)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
NDP Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate
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Code : 2JAP   PDBj   RCSB PDB   PDBe
Header : OXIDOREDUCTASE
Title : Clavulanic Acid Dehydrogenase: Structural and Biochemical Analysis of the Final Step in the Biosynthesis of the beta-Lactamase Inhibitor Clavulanic acid
Release Data : 2007-02-20
Compound :
mol_id molecule chains synonym
1 CLAVALDEHYDE DEHYDROGENASE A,B,C,D CLAVULANIC ACID DEHYDROGENASE
Source :
mol_id organism_scientific expression_system
1 STREPTOMYCES CLAVULIGERUS  (taxid:1901) ESCHERICHIA COLI  (taxid:469008)
strain: NRRL3585
expression_system_strain: BL21(DE3)
expression_system_plasmid: PET24A
Authors : MacKenzie, A.K., Kershaw, N.J., Hernandez, H., Robinson, C.V., Schofield, C.J., Andersson, I.
Keywords : SHORT-CHAIN DEHYDROGENASE/REDUCTASE, OXIDOREDUCTASE, ANTIBIOTIC BIOSYNTHESIS, BETA-LACTAMASE INHIBITOR
Exp. method : X-RAY DIFFRACTION ( 2.10 Å )
Citation :

Clavulanic Acid Dehydrogenase: Structural and Biochemical Analysis of the Final Step in the Biosynthesis of the Beta-Lactamase Inhibitor Clavulanic Acid

Mackenzie, A.K.,Kershaw, N.J.,Hernandez, H.  et al.
(2007)  Biochemistry  46 : 1523

PubMed: 17279617
DOI: 10.1021/BI061978X

Chain : A, B, C, D
UniProt : Q9LCV7 (Q9LCV7_STRCL)
Reaction : -