Het-PDB Navi2 (PDB: 2IY5)

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Ligands
Code	Name		Style	Show	Link
FYA	Adenosine-5'-[phenylalaninol-phosphate]				PoSSuM
MG	Magnesium ion				PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 2IY5

Code :

2IY5 PDBj RCSB PDB PDBe

Header :

LIGASE

Title :

PHENYLALANYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS complexed with tRNA and a phenylalanyl-adenylate analog

Release Data :

2006-09-06

Compound :

mol_id	molecule	chains	synonym
1	PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN	A	PHENYLALANYL-TRNA SYNTHETASE, PHERS, PHENYLALANINE-TRNA LIGASE ALPHA CHAIN
	ec: 6.1.1.20

mol_id	molecule	chains	synonym
2	PHENYLALANYL-TRNA SYNTHETASE BETA CHAIN	B	PHENYLALANYL-TRNA SYNTHETASE, PHERS, PHENYLALANINE-TRNA LIGASE BETA CHAIN
	ec: 6.1.1.20

mol_id	molecule	chains
3	TRNAPHE	T

Source :

mol_id	organism_scientific
1	THERMUS THERMOPHILUS (taxid:300852)
	strain: HB8

mol_id	organism_scientific
2	THERMUS THERMOPHILUS (taxid:300852)
	strain: HB8

mol_id	organism_scientific
3	THERMUS THERMOPHILUS (taxid:300852)
	strain: HB8

Authors :

Moor, N., Kotik-Kogan, O., Tworowski, D., Sukhanova, M., Safro, M.

Keywords :

CLASS II AMINOACYL-TRNA SYNTHETASE, LIGASE, RBD DOMIN, MAGNESIUM, SH3 DOMAIN, PHENYLALANYL-TRNA SYNTHETASE, THERMUS THERMOPHILUS, PROTEIN BIOSYNTHESIS, METAL-BINDING, NUCLEOTIDE-BINDING, RNA-BINDING, ATP-BINDING, TRNA-BINDING, HELIX-TURN-HELIX MOTIF, AMINOACYL-TRNA SYNTHETASE

Exp. method :

X-RAY DIFFRACTION ( 3.10 Å )

Citation :

The crystal structure of the ternary complex of phenylalanyl-tRNA synthetase with tRNAPhe and a phenylalanyl-adenylate analogue reveals a conformational switch of the CCA end.

Moor, N.,Kotik-Kogan, O.,Tworowski, D. et al.
(2006) Biochemistry 45 : 10572 - 10583

PubMed: 16939209
DOI: 10.1021/bi060491l

PDB ID: 2IY5

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