Brand  (β version)

PDB ID: 2I61

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Ligands
Code Name Style Show Link
ACY Acetic acid PoSSuM
CO2 Carbon dioxide PoSSuM
EDO 1,2-ethanediol PoSSuM
LI Lithium ion PoSSuM
SO4 Sulfate ion PoSSuM
Non-standard Residues
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Structure summary

Code : 2I61   PDBj   RCSB PDB   PDBe
Header : TOXIN
Title : Depressant anti-insect neurotoxin, LqhIT2 from Leiurus quinquestriatus hebraeus
Release Data : 2006-12-26
Compound :
mol_id molecule chains synonym
1 Insect toxin 2 A Lqh IT2, LqhIT2, LqhIT2-44, anti-insect depressant neurotoxin
fragment: Peptide modifier of voltage-gated sodium channels
Source :
mol_id organism_scientific expression_system
1 Leiurus quinquestriatus hebraeus  (taxid:6884) Escherichia coli BL21  (taxid:511693)
strain: hebraeus
expression_system_strain: BL21
expression_system_vector_type: Plasmid
expression_system_plasmid: pET11c
Authors : Frolow, F., Gurevitz, M., Karbat, I., Turkov, M., Gordon, D.
Keywords : Scorpion toxin, depressant, anti-insect, sodium channel modifer, TOXIN
Exp. method : X-RAY DIFFRACTION ( 1.200 Å )
Citation :

X-ray Structure and Mutagenesis of the Scorpion Depressant Toxin LqhIT2 Reveals Key Determinants Crucial for Activity and Anti-Insect Selectivity.

Karbat, I.,Turkov, M.,Cohen, L.  et al.
(2007)  J.Mol.Biol.  366 : 586 - 601

PubMed: 17166514
DOI: 10.1016/j.jmb.2006.10.085

Reaction

Chain : A
UniProt : Q26292 (SIX2_LEIHE)
Reaction : -