Het-PDB Navi2 (PDB: 2HKA)

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Ligands
Code	Name		Style	Show	Link
ACT	Acetate ion				PoSSuM

Non-standard Residues
Code	Name	Show

Glycosylation
Code	Name	Emphasize
NAG	2-acetamido-2-deoxy-beta-D-glucopyranose

Modification
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Download interaction data: 2HKA

Code :

2HKA PDBj RCSB PDB PDBe

Header :

LIPID BINDING PROTEIN

Title :

Crystal structure of bovine NPC2 and cholesterol sulfate complex

Release Data :

2007-06-26

Compound :

mol_id	molecule	chains	synonym
1	Epididymal secretory protein E1	A,B,C	Niemann Pick type C2 protein homolog, NPC2, EPV20

Source :

mol_id	organism_scientific	organism_common
1	Bos taurus (taxid:9913)	Cattle
	secretion: MILK

Authors :

Xu, S., Gu, L., Benoff, B., Stock, A.M.

Keywords :

BETA BARREL, LIPID BINDING PROTEIN

Exp. method :

X-RAY DIFFRACTION ( 1.81 Å )

Citation :

Structural Basis of Sterol Binding by NPC2, a Lysosomal Protein Deficient in Niemann-Pick Type C2 Disease

Xu, S.,Benoff, B.,Liou, H.-L. et al.
(2007) J.Biol.Chem. 282 : 23525 - 23531

Chain :

A, B, C

UniProt :

P79345 (NPC2_BOVIN)

Reaction:	EC:	Evidence:
Reaction:	Physiological Direction:	Evidence:
cholesterol(in) = cholesterol(out)	-	PubMed:17552909
cholesterol(in) = cholesterol(out)	-	PubMed:17552909

PDB ID: 2HKA