Brand  (β version)

color scheme of protein:

hetatm:

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information
centroid:
interaction residue:

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Ligands
Code Name Link
GD Gadolinium atom
SO4 Sulfate ion
Code : 2HHM
Header : HYDROLASE
Title : STRUCTURE OF INOSITOL MONOPHOSPHATASE, THE PUTATIVE TARGET OF LITHIUM THERAPY
Release Data : 1993-10-31
Compound :
mol_id molecule chains
1 INOSITOL MONOPHOSPHATASE A,B
ec: 3.1.3.25
Source :
mol_id organism_scientific organism_common
1 Homo sapiens  (taxid:9606) Human
organ: BRAIN
Authors : Bone, R.
Keywords : HYDROLASE
Exp. method : X-RAY DIFFRACTION ( 2.1 Å )
Citation :

Structure of inositol monophosphatase, the putative target of lithium therapy.

Bone, R.,Springer, J.P.,Atack, J.R.
(1992)  Proc.Natl.Acad.Sci.USA  89 : 10031 - 10035

PubMed: 1332026
DOI: 10.1073/pnas.89.21.10031

C/DNA Cloning of Human and Rat Brain Myo-Inositol Monophosphatase: Expression and Characterization of the Human Recombinant Enzyme

Mcallister, G.,Whiting, P.,Hammond, E.A.  et al.
(1992)  Biochem.J.  284 : 749

Chain : A, B
UniProt : P29218 (IMPA1_HUMAN)
Reaction : Myo-inositol phosphate + H(2)O = myo-inositol + phosphate.
Alpha-D-galactose 1-phosphate + H(2)O = D- galactose + phosphate.