Het-PDB Navi2 (PDB: 2HDU)

The number of atoms exceeds 100,000.
So, it can not be displayed here.

Select unit:

Select hetatm:

information

centroid:

interaction residue:

Select chain: Sequence Hide other chain(s)

Data format:

Color scheme of protein:

Ligands
Code	Name		Style	Show	Link
F12	2-(acetylamino)thiophene-3-carboxylic acid				PoSSuM

Non-standard Residues
Code	Name	Show

Glycosylation
Code	Name	Emphasize

Modification
Code	Name	Show

Download interaction data: 2HDU

Code :

2HDU PDBj RCSB PDB PDBe

Header :

HYDROLASE

Title :

AmpC beta-lactamase in complex with 2-acetamidothiophene-3-carboxylic acid

Release Data :

2006-11-07

Compound :

mol_id	molecule	chains	synonym
1	Beta-lactamase	A,B	Cephalosporinase
	ec: 3.5.2.6

Source :

mol_id	organism_scientific	expression_system
1	Escherichia coli K12 (taxid:83333)	Escherichia coli (taxid:562)
	strain: K-12 gene: ampC expression_system_strain: JM109

Authors :

Babaoglu, K., Shoichet, B.K.

Keywords :

AmpC beta-lactamase fragment-based drug design, HYDROLASE

Exp. method :

X-RAY DIFFRACTION ( 1.490 Å )

Citation :

Deconstructing fragment-based inhibitor discovery

Babaoglu, K.,Shoichet, B.K.
(2006) Nat.Chem.Biol. 2 : 720 - 723

Chain :

A, B

UniProt :

P00811 (AMPC_ECOLI)

Reaction:	EC:	Evidence:
Reaction:	Physiological Direction:	Evidence:
a beta-lactam + H2O = a substituted beta-amino acid	3.5.2.6	PROSITE- ProRule:PRU10102
a beta-lactam + H2O = a substituted beta-amino acid	-	PROSITE- ProRule:PRU10102

PDB ID: 2HDU