PDB ID: 2HD6
Hetero Atom Contents
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Color scheme of protein:
Code | Name | Style | Show | Link | |
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BOS | N-[4-(aminosulfonyl)phenyl]-2-mercaptobenzamide | PoSSuM | |||
CL | Chloride ion | PoSSuM | |||
GOL | Glycerol | PoSSuM | |||
MBO | Mercuribenzoic acid | PoSSuM | |||
ZN | Zinc ion | PoSSuM |
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Download interaction data: 2HD6
Structure summary
Code : | 2HD6 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | LYASE | ||||||||||||
Title : | Crystal structure of the human carbonic anhydrase II in complex with a hypoxia-activatable sulfonamide. | ||||||||||||
Release Data : | 2006-10-03 | ||||||||||||
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Authors : | De Simone, G., Vitale, R.M., Di Fiore, A., Pedone, C. | ||||||||||||
Keywords : | PROTEIN-INHIBITOR COMPLEX, LYASE | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.80 Å ) | ||||||||||||
Citation : |
Carbonic anhydrase inhibitors: Hypoxia-activatable sulfonamides incorporating disulfide bonds that target the tumor-associated isoform IX.
De Simone, G.,Vitale, R.M.,Di Fiore, A.
et al.
PubMed: 16942027 Refined structure of human carbonic anhydrase II at 2.0 A resolution.
Eriksson, A.E.,Jones, T.A.,Liljas, A.
PubMed: 3151019 |
Reaction
Chain : | A | ||||||||||||
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UniProt : | P00918 (CAH2_HUMAN) | ||||||||||||
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