PDB ID: 2H4W
Hetero Atom Contents
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Structure summary
Code : | 2H4W PDBj RCSB PDB PDBe | ||||||||||||||||||||||||||||||||||||
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Header : | HYDROLASE/HYDROLASE INHIBITOR | ||||||||||||||||||||||||||||||||||||
Title : | Crystal structure of human caspase-1 (Glu390->Asp) in complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-propionylamino]-4-oxo-pentanoic acid (z-VAD-FMK) | ||||||||||||||||||||||||||||||||||||
Release Data : | 2008-03-11 | ||||||||||||||||||||||||||||||||||||
Compound : |
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Source : |
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Authors : | Scheer, J.M., Wells, J.A., Romanowski, M.J. | ||||||||||||||||||||||||||||||||||||
Keywords : | allosteric site, dimer interface, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX | ||||||||||||||||||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.00 Å ) | ||||||||||||||||||||||||||||||||||||
Citation : |
An allosteric circuit in caspase-1.
Datta, D.,Scheer, J.M.,Romanowski, M.J.
et al.
PubMed: 18590738 |
Reaction
Chain : | B | ||||||||
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UniProt : | P29466 (CASP1_HUMAN) | ||||||||
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