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Ligands
Code Name Style Show Link
F6R Fructose -6-phosphate
ZN Zinc ion
Non-standard Residues
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Glycosylation
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Code : 2GC2   PDBj   RCSB PDB   PDBe
Header : ISOMERASE
Title : The crystal structure of phosphoglucose isomerase from Pyrococcus furiosus in complex with Fructose 6-phosphate and zinc
Release Data : 2006-04-11
Compound :
mol_id molecule chains synonym
1 Glucose-6-phosphate isomerase A,B GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI
ec: 5.3.1.9
Source :
mol_id organism_scientific expression_system
1 Pyrococcus furiosus  (taxid:2261) Escherichia coli BL21  (taxid:511693)
gene: pgiA
expression_system_strain: BL21
expression_system_vector_type: plasmid
expression_system_plasmid: pLUW557
Authors : Berrisford, J.M., Rice, D.W., Baker, P.J.
Keywords : cupin, phosphoglucose isomerase, fructose 6-phosphate, ISOMERASE
Exp. method : X-RAY DIFFRACTION ( 2.100 Å )
Citation :

Evidence Supporting a cis-enediol-based Mechanism for Pyrococcus furiosus Phosphoglucose Isomerase

Berrisford, J.M.,Hounslow, A.M.,Akerboom, J.  et al.
(2006)  J.Mol.Biol.  358 : 1353 - 1366

PubMed: 16580686
DOI: 10.1016/j.jmb.2006.03.015

Chain : A, B
UniProt : P83194 (G6PI_PYRFU)
Reaction: EC: Evidence:
Physiological Direction:
alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate 5.3.1.9 -
-