Brand  (β version)

color scheme of protein:

hetatm:

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information
centroid:
interaction residue:

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Ligands
Code Name Link
CP Phosphoric acid mono(formamide)ester
AN0 N-acetyl-L-norvaline
SO4 Sulfate ion
Code : 2G7M
Header : TRANSFERASE
Title : Crystal structure of B. fragilis N-succinylornithine transcarbamylase P90E mutant complexed with carbamoyl phosphate and N-acetylnorvaline
Release Data : 2007-03-06
Compound :
mol_id molecule chains
1 putative ornithine carbamoyltransferase X,Y,Z,C,D,E
ec: 2.1.3.-
mutation: P90E, T242L
Source :
mol_id organism_scientific expression_system
1 Bacteroides fragilis  (taxid:817) Escherichia coli BL21(DE3)  (taxid:469008)
gene: argF'
expression_system_strain: BL21(DE3)
expression_system_vector_type: PLASMID
expression_system_plasmid: pET28a
Authors : Shi, D., Yu, X., Roth, L., Morizono, H., Allewell, N.M., Tuchman, M.
Keywords : Alpha/beta, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 2.90 Å )
Citation :

A single mutation in the active site swaps the substrate specificity of N-acetyl-L-ornithine transcarbamylase and N-succinyl-L-ornithine transcarbamylase.

Shi, D.,Yu, X.,Cabrera-Luque, J.  et al.
(2007)  Protein Sci.  16 : 1689 - 1699

PubMed: 17600144
DOI: 10.1110/ps.072919907