Het-PDB Navi2 (PDB: 2FS9)

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Ligands
Code	Name		Style	Show	Link
C4A	Ethyl {(1s)-5-amino-1-[(5-{4-[(2,3-dihydro-1h-inden-2-ylamino)carbonyl]benzyl}-1,2,4-oxadiazol-3-yl)carbonyl]pentyl}carbamate				PoSSuM

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Download interaction data: 2FS9

Code :

2FS9 PDBj RCSB PDB PDBe

Header :

HYDROLASE

Title :

Human beta tryptase II with inhibitor CRA-28427

Release Data :

2006-03-07

Compound :

mol_id	molecule	chains	synonym
1	Tryptase beta-2	A,B,C,D	Tryptase-2, Tryptase II
	ec: 3.4.21.59

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Pichia pastoris (taxid:4922)
	gene: TPSB2, TPS2

Authors :

Somoza, J.R.

Keywords :

serine protease, serine proteinase, 28427, HYDROLASE

Exp. method :

X-RAY DIFFRACTION ( 2.300 Å )

Citation :

Structure-guided design of Peptide-based tryptase inhibitors.

McGrath, M.E.,Sprengeler, P.A.,Hirschbein, B. et al.
(2006) Biochemistry 45 : 5964 - 5973

PDB ID: 2FS9