Het-PDB Navi2 (PDB: 2FHR)

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Ligands
Code	Name	Link
GOL	Glycerol	PoSSuM
SO4	Sulfate ion	PoSSuM
FSI	5-acetamido-3,5-dideoxy-3-fluoro-D-erythro-alpha-L-manno-non-2-ulopyranosonic acid	PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 2FHR

Code :

2FHR PDBj RCSB PDB PDBe

Header :

HYDROLASE

Title :

Trypanosoma Rangeli Sialidase In Complex With 2,3- Difluorosialic Acid (Covalent Intermediate)

Release Data :

2006-01-17

Compound :

mol_id	molecule	chains
1	sialidase	A
	ec: 3.2.1.18

Source :

mol_id	organism_scientific	expression_system
1	Trypanosoma rangeli (taxid:5698)	Escherichia coli (taxid:562)
	expression_system_strain: TOP10 expression_system_vector_type: plasmid expression_system_plasmid: pTrcHisA

Authors :

Amaya, M.F., Alzari, P.M., Buschiazzo, A.

Keywords :

BETA-PROPELLER, COVALENT ENZYME-INTERMEDIATE COMPLEX, BETA-SANDWICH, HYDROLASE

Exp. method :

X-RAY DIFFRACTION ( 2.20 Å )

Citation :

Structural and Kinetic Analysis of Two Covalent Sialosyl-Enzyme Intermediates on Trypanosoma rangeli Sialidase.

Watts, A.G.,Oppezzo, P.,Withers, S.G. et al.
(2006) J.Biol.Chem. 281 : 4149 - 4155

PDB ID: 2FHR