Brand  (β version)

PDB ID: 2DQO

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Ligands
Code Name Style Show Link
BA Barium ion PoSSuM
CMY (6-aminohexyl)carbamic acid PoSSuM
NA Sodium ion PoSSuM
Non-standard Residues
Code Name Show
OMU O2'-methyluridine 5'-monophosphate
Glycosylation
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Modification
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Structure summary

Code : 2DQO   PDBj   RCSB PDB   PDBe
Header : DNA-RNA HYBRID
Title : Crystal Structure of D(CXCTXCTTC):R(gaagaagag) Where X is 5-(N-aminohexyl)carbamoyl-2'-O-methyluridine
Release Data : 2007-04-17
Compound :
mol_id molecule chains
1 DNA (5'-D(*DCP*(OMU)P*DCP*DTP*(OMU)P*DCP*DTP*DTP*DC)-3') A
mol_id molecule chains
2 RNA (5'-R(*GP*AP*AP*GP*AP*AP*GP*AP*G)-3') B
Source :
mol_id organism_scientific
1
synthetic: yes
other_details: synthetic constructs
mol_id organism_scientific
2
synthetic: yes
other_details: synthetic constructs
Authors : Juan, E.C.M., Kondo, J., Ito, T., Ueno, Y., Matsuda, A., Takenaka, A.
Keywords : modified nucleotide, 5-(N-aminohexyl)carbamoyl-2'-O-methyluridine, A-form RNA:DNA hybrid duplex, DNA-RNA HYBRID
Exp. method : X-RAY DIFFRACTION ( 2.3 Å )
Citation :

Crystal structures of DNA:DNA and DNA:RNA duplexes containing 5-(N-aminohexyl)carbamoyl-modified uracils reveal the basis for properties as antigene and antisense molecules

Juan, E.C.M.,Kondo, J.,Kurihara, T.  et al.
(2007)  Nucleic Acids Res.  35 : 1969 - 1977

PubMed: 17341465
DOI: 10.1093/nar/gkl821