Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain:

Ligands
Code Name Link
CL Chloride ion
Modified Residues
Code Name Link
0AK (2s)-2-amino-4-(2-chloroethoxy)-4-oxobutanoic acid
Code : 2DHD
Header : DEHALOGENASE
Title : CRYSTALLOGRAPHIC ANALYSIS OF THE CATALYTIC MECHANISM OF HALOALKANE DEHALOGENASE
Release Data : 1994-07-31
Compound :
mol_id molecule chains
1 HALOALKANE DEHALOGENASE A
ec: 3.8.1.5
Source :
mol_id organism_scientific
1 Xanthobacter autotrophicus  (taxid:280)
Authors : Verschueren, K.H.G., Dijkstra, B.W.
Keywords : DEHALOGENASE
Exp. method : X-RAY DIFFRACTION ( 2.13 Å )
Citation :

Crystallographic analysis of the catalytic mechanism of haloalkane dehalogenase.

Verschueren, K.H.,Seljee, F.,Rozeboom, H.J.  et al.
(1993)  Nature  363 : 693 - 698

PubMed: 8515812
DOI: 10.1038/363693a0

Crystal Structure of Haloalkane Dehalogenase: An Enzyme to Detoxify Halogenated Alkanes

Franken, S.M.,Rozeboom, H.J.,Kalk, K.H.  et al.
(1991)  Embo J.  10 : 1297

Crystallization of Haloalkane Dehalogenase from Xanthobacter Autotrophicus Gj10

Rozeboom, H.J.,Kingma, J.,Janssen, D.B.  et al.
(1988)  J.Mol.Biol.  200 : 611

Chain : A
UniProt : P22643 (DHLA_XANAU)
Reaction : 1-haloalkane + H(2)O = a primary alcohol + halide.
1,2-dichloroethane + H(2)O = 2-chloroethanol + hydrogen chloride.