Brand  (β version)

PDB ID: 2DEM

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Ligands
Code Name Style Show Link
2HP Dihydrogenphosphate ion PoSSuM
EOH Ethanol PoSSuM
GOL Glycerol PoSSuM
SF4 Iron/sulfur cluster PoSSuM
ORP 2-deoxy-5-phosphono-ribose PoSSuM
Non-standard Residues
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Glycosylation
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Structure summary

Code : 2DEM   PDBj   RCSB PDB   PDBe
Header : HYDROLASE/DNA
Title : Crystal structure of Uracil-DNA glycosylase in complex with AP:A containing DNA
Release Data : 2007-04-24
Compound :
mol_id molecule chains
1 5'-D(*AP*TP*GP*TP*TP*GP*CP*(D1P)P*TP*TP*AP*GP*TP*CP*C)-3' C
mol_id molecule chains
2 5'-D(*GP*GP*AP*CP*TP*AP*AP*AP*GP*CP*AP*AP*CP*A)-3' D
mol_id molecule chains
3 uracil-DNA glycosylase A
ec: 3.2.2.-
Source :
mol_id organism_scientific
1 Synthetic construct  (taxid:32630)
synthetic: yes
mol_id organism_scientific
2 Synthetic construct  (taxid:32630)
synthetic: yes
mol_id organism_scientific expression_system
3 Thermus thermophilus  (taxid:300852) Escherichia coli BL21(DE3)  (taxid:469008)
strain: HB8
gene: ttUDGB
expression_system_strain: BL21(DE3)
expression_system_vector_type: PLASMID
expression_system_plasmid: pET11a
Authors : Kosaka, H., Nakagawa, N., Masui, R., Hoseki, J., Kuramitsu, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Keywords : base excision repair, uracil-DNA glycosylase, Iron/Sulfur cluster, Thermophile, Structural Genomics, NPPSFA, National Project on Protein Structural and Functional Analyses, RIKEN Structural Genomics/Proteomics Initiative, RSGI, HYDROLASE-DNA COMPLEX
Exp. method : X-RAY DIFFRACTION ( 1.95 Å )
Citation :

Crystal structure of family 5 uracil-DNA glycosylase bound to DNA.

Kosaka, H.,Hoseki, J.,Nakagawa, N.  et al.
(2007)  J.Mol.Biol.  373 : 839 - 850

PubMed: 17870091
DOI: 10.1016/j.jmb.2007.08.022