Brand  (β version)

  The number of atoms exceeds 100,000.
  So, it can not be displayed here.

Select unit:

Select hetatm:   

close
information
centroid:
interaction residue:

Select chain:   Sequence  

Data format:   

Color scheme of protein:

Ligands
Code Name Style Show Link
ADP Adenosine-5'-diphosphate
DGT 2'-deoxyguanosine-5'-triphosphate
MG Magnesium ion
Non-standard Residues
Code Name Show
Glycosylation
Code Name Emphasize
Modification
Code Name Show
Code : 2CVX   PDBj   RCSB PDB   PDBe
Header : OXIDOREDUCTASE
Title : Structures of Yeast Ribonucleotide Reductase I
Release Data : 2006-03-07
Compound :
mol_id molecule chains synonym
1 Ribonucleoside-diphosphate reductase large chain 1 A Ribonucleotide reductase I
ec: 1.17.4.1
Source :
mol_id organism_scientific organism_common expression_system
1 Saccharomyces cerevisiae  (taxid:4932) Baker's yeast Escherichia coli BL21(DE3)  (taxid:469008)
expression_system_strain: Bl21(DE3)
expression_system_vector_type: PLASMID
expression_system_plasmid: pWJ751-3
Authors : Xu, H., Faber, C., Uchiki, T., Fairman, J.W., Racca, J., Dealwis, C.
Keywords : Eukaryotic, Ribonucleotide Reductase, dNTP Regulation, Oxidoreductase
Exp. method : X-RAY DIFFRACTION ( 2.20 Å )
Citation :

Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation

Xu, H.,Faber, C.,Uchiki, T.  et al.
(2006)  Proc.Natl.Acad.Sci.Usa  103 : 4022 - 4027

PubMed: 16537479
DOI: 10.1073/pnas.0600443103

Chain : A
UniProt : P21524 (RIR1_YEAST)
Reaction: EC: Evidence:
Physiological Direction:
[thioredoxin]-disulfide + a 2'-deoxyribonucleoside 5'- diphosphate + H2O = [thioredoxin]-dithiol + a ribonucleoside 5'- diphosphate 1.17.4.1 -
-