Het-PDB Navi2 (PDB: 2CSN)

The number of atoms exceeds 100,000.
So, it can not be displayed here.

Select unit:

Select hetatm:

information

centroid:

interaction residue:

Select chain: Sequence Hide other chain(s)

Data format:

Color scheme of protein:

Ligands
Code	Name		Style	Show	Link
CKI	N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide				PoSSuM
SO4	Sulfate ion				PoSSuM

Non-standard Residues
Code	Name	Show

Glycosylation
Code	Name	Emphasize

Modification
Code	Name	Show

Download interaction data: 2CSN

Code :

2CSN PDBj RCSB PDB PDBe

Header :

PROTEIN KINASE

Title :

BINARY COMPLEX OF CASEIN KINASE-1 WITH CKI7

Release Data :

1996-03-08

Compound :

mol_id	molecule	chains
1	CASEIN KINASE-1	A
	ec: 2.7.1.- fragment: CATALYTIC CORE RESIDUES 2 - 298

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Schizosaccharomyces pombe (taxid:4896)	Fission yeast	Escherichia coli (taxid:562)

Authors :

Xu, R.-M., Cheng, X.

Keywords :

CASEIN KINASE-1, PROTEIN KINASE

Exp. method :

X-RAY DIFFRACTION ( 2.50 Å )

Citation :

Structural basis for selectivity of the isoquinoline sulfonamide family of protein kinase inhibitors.

Xu, R.M.,Carmel, G.,Kuret, J. et al.
(1996) Proc.Natl.Acad.Sci.USA 93 : 6308 - 6313

Crystal Structure of Casein Kinase-1, a Phosphate-Directed Protein Kinase

Xu, R.-M.,Carmel, G.,Sweet, R.M. et al.
(1995) Embo J. 14 : 1015

Expression, Purification, Crystallization, and Preliminary X-Ray Analysis of Casein Kinase-1 from Schizosaccharomyces Pombe

Carmel, G.,Leichus, B.,Cheng, X. et al.
(1994) J.Biol.Chem. 269 : 7304

Chain :

UniProt :

P40233 (CKI1_SCHPO)

Reaction:	EC:	Evidence:
Reaction:	Physiological Direction:	Evidence:
ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl- [protein]	2.7.11.1	-
	-	-
ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L- threonyl-[protein]	2.7.11.1	-
	-	-

PDB ID: 2CSN