PDB ID: 2CMA
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Structure summary
Code : | 2CMA PDBj RCSB PDB PDBe | ||||||||||||
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Header : | HYDROLASE | ||||||||||||
Title : | Structural Basis for Inhibition of Protein Tyrosine Phosphatase 1B by Isothiazolidinone Heterocyclic Phosphonate Mimetics | ||||||||||||
Release Data : | 2006-08-17 | ||||||||||||
Compound : |
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Source : |
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Authors : | Ala, P.J., Gonneville, L., Hillman, M.C., Becker-Pasha, M., Wei, M., Reid, B.G., Klabe, R., Yue, E.W., Wayland, B., Douty, B., Combs, A.P., Polam, P., Wasserman, Z., Bower, M., Burn, T.C., Hollis, G.F., Wynn, R. | ||||||||||||
Keywords : | POLYMORPHISM, PHOSPHORYLATION, PROTEIN PHOSPHATASE, ENDOPLASMIC RETICULUM, OXIDATION, HYDROLASE, ACETYLATION, PHOSPHATASE | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.3 Å ) | ||||||||||||
Citation : |
Structural Basis for Inhibition of Protein-Tyrosine Phosphatase 1B by Isothiazolidinone Heterocyclic Phosphonate Mimetics.
Ala, P.J.,Gonneville, L.,Hillman, M.C.
et al.
PubMed: 16916797 |
Reaction
Chain : | A | ||||||||
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UniProt : | P18031 (PTN1_HUMAN) | ||||||||
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