Brand  (β version)

color scheme of protein:

hetatm:

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information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
PC Phosphocholine
Code : 2CKQ
Header : TRANSFERASE
Title : Crystal structure of Human Choline Kinase alpha 2 in complex with Phosphocholine
Release Data : 2006-10-04
Compound :
mol_id molecule chains synonym
1 CHOLINE KINASE ALPHA A,B CK, CHETK-ALPHA, ETHANOLAMINE KINASE, EK
ec: 2.7.1.32, 2.7.1.82
fragment: SPLICE ISOFORM 2, RESIDUES 50-439
Source :
mol_id organism_scientific organism_common expression_system
1 HOMO SAPIENS  (taxid:9606) HUMAN ESCHERICHIA COLI  (taxid:469008)
expression_system_strain: BL21(DE3)
expression_system_vector_type: PLASMID
expression_system_vector: PGEX-RB
Authors : Malito, E., Lavie, A.
Keywords : TRANSFERASE, PHOSPHATIDYLCHOLINE, PHOSPHOLIPID SYNTHESIS
Exp. method : X-RAY DIFFRACTION ( 2.40 Å )
Citation :

Elucidation of Human Choline Kinase Crystal Structures in Complex with the Products Adp or Phosphocholine.

Malito, E.,Sekulic, N.,Too, W.C.  et al.
(2006)  J.Mol.Biol.  364 : 136

PubMed: 17007874
DOI: 10.1016/J.JMB.2006.08.084

Chain : A, B
UniProt : P35790 (CHKA_HUMAN)
Reaction : ATP + choline = ADP + phosphocholine.
ATP + ethanolamine = ADP + O- phosphoethanolamine.