PDB ID: 2C5N
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Structure summary
Code : | 2C5N PDBj RCSB PDB PDBe | ||||||||||||||||||||
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Header : | TRANSFERASE | ||||||||||||||||||||
Title : | Differential Binding Of Inhibitors To Active And Inactive Cdk2 Provides Insights For Drug Design | ||||||||||||||||||||
Release Data : | 2006-03-01 | ||||||||||||||||||||
Compound : |
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Source : |
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Authors : | Kontopidis, G., McInnes, C., Pandalaneni, S.R., McNae, I., Gibson, D., Mezna, M., Thomas, M., Wood, G., Wang, S., Walkinshaw, M.D., Fischer, P.M. | ||||||||||||||||||||
Keywords : | DIFFERENTIAL INHIBITION, TRANSFERASE, CDK2, ATP-BINDING, CELL CYCLE, CELL DIVISION, POLYMORPHISM, PHOSPHORYLATION, NUCLEOTIDE-BINDING, SERINE/THREONINE-PROTEIN, KINASE, MITOSIS, CYCLIN | ||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.10 Å ) | ||||||||||||||||||||
Citation : |
Differential Binding of Inhibitors to Active and Inactive Cdk2 Provides Insights for Drug Design.
Kontopidis, G.,Mcinnes, C.,Pandalaneni, S.R.
et al.
PubMed: 16492568 |
Reaction
Chain : | A, C | ||||||||||||
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UniProt : | P24941 (CDK2_HUMAN) | ||||||||||||
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Chain : | B, D |
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UniProt : | P20248 (CCNA2_HUMAN) |
Reaction : | - |