Brand  (β version)

PDB ID: 2C3Y

Hetero Atom Contents

  The number of atoms exceeds 100,000.
  So, it can not be displayed here.

Select unit:

Select hetatm:   

close
information
centroid:
interaction residue:

Select chain:   Sequence  

Data format:   

Color scheme of protein:

Ligands
Code Name Style Show Link
CA Calcium ion PoSSuM
CO2 Carbon dioxide PoSSuM
HTL 2-acetyl-thiamine diphosphate PoSSuM
MG Magnesium ion PoSSuM
SF4 Iron/sulfur cluster PoSSuM
Non-standard Residues
Code Name Show
Glycosylation
Code Name Emphasize
Modification
Code Name Show

Structure summary

Code : 2C3Y   PDBj   RCSB PDB   PDBe
Header : OXIDOREDUCTASE
Title : CRYSTAL STRUCTURE OF THE RADICAL FORM OF PYRUVATE:FERREDOXIN OXIDOREDUCTASE FROM Desulfovibrio africanus
Release Data : 2006-02-15
Compound :
mol_id molecule chains
1 PYRUVATE-FERREDOXIN OXIDOREDUCTASE A,B
ec: 1.2.7.1
other_details: COMPLEXED WITH IRON/SULFUR CLUSTER, THIAMIN DIPHOSPHATE, CRYSTAL SOAKED OVERNIGHT WITH PYRUVATE
Source :
mol_id organism_scientific
1 DESULFOVIBRIO AFRICANUS  (taxid:873)
Authors : Cavazza, C., Contreras-Martel, C., Pieulle, L., Chabriere, E., Hatchikian, E.C., Fontecilla-Camps, J.C.
Keywords : OXIDOREDUCTASE, 4FE-4S, IRON, IRON-SULFUR, IRON-SULFUR CLUSTER, PYRUVATE CATABOLISM, TPP-DEPENDENT ENZYME, METAL-BINDING, ELECTRON TRANSPORT
Exp. method : X-RAY DIFFRACTION ( 1.93 Å )
Citation :

Flexibility of Thiamine Diphosphate Revealed by Kinetic Crystallographic Studies of the Reaction of Pyruvate-Ferredoxin Oxidoreductase with Pyruvate.

Cavazza, C.,Contreras-Martel, C.,Pieulle, L.  et al.
(2006)  Structure  14 : 217

PubMed: 16472741
DOI: 10.1016/J.STR.2005.10.013

Crystal Structure of the Free Radical Intermediate of Pyruvate:Ferredoxin Oxidoreductase.

Chabriere, E.,Vernede, X.,Guigliarelli, B.  et al.
(2001)  Science  2559 : 294

PubMed: 11752578
DOI: 10.1126/SCIENCE.1066198

Reaction

Chain : A, B
UniProt : P94692 (PFOR_DESAF)
Reaction: EC: Evidence:
Physiological Direction:
CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin] 1.2.7.1 PubMed:7612653
-