PDB ID: 2BUC
Hetero Atom Contents
The number of atoms exceeds 100,000. So, it can not be displayed here.
Select unit:
Select hetatm:
Select chain: Sequence
Data format:
Color scheme of protein:
Code | Name | Style | Show | Link | |
---|---|---|---|---|---|
008 | (S)-2-[(R)-3-amino-4-(2-fluoro-phenyl)-butyryl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid amide | PoSSuM | |||
SO4 | Sulfate ion | PoSSuM |
Code | Name | Show |
---|
Code | Name | Emphasize |
---|---|---|
NAG | 2-acetamido-2-deoxy-beta-D-glucopyranose |
Code | Name | Show |
---|
Download interaction data: 2BUC
Structure summary
Code : | 2BUC PDBj RCSB PDB PDBe | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Header : | HYDROLASE/INHIBITOR | ||||||||||||
Title : | Crystal Structure Of Porcine Dipeptidyl Peptidase IV (CD26) in Complex with a Tetrahydroisoquinoline Inhibitor | ||||||||||||
Release Data : | 2006-01-23 | ||||||||||||
Compound : |
|
||||||||||||
Source : |
|
||||||||||||
Authors : | Nordhoff, S., Cerezo-Galvez, S., Feurer, A., Hill, O., Matassa, V.G., Metz, G., Rummey, C., Thiemann, M., Edwards, P.J. | ||||||||||||
Keywords : | HYDROLASE/INHIBITOR, COMPLEX (HYDROLASE-INHIBITOR), DPP-IV, DIABETES MELLITUS, DRUG DESIGN, HYDROLASE, SERINE PROTEASE, AMINOPEPTIDASE, GLYCOPROTEIN, PROTEASE, SIGNAL-ANCHOR, TRANSMEMBRANE, COMPLEX, HYDROLASE-INHIBITOR complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.50 Å ) | ||||||||||||
Citation : |
The reversed binding of beta-phenethylamine inhibitors of DPP-IV: X-ray structures and properties of novel fragment and elaborated inhibitors.
Nordhoff, S.,Cerezo-Galvez, S.,Feurer, A.
et al.
PubMed: 16376544 |
Reaction
Chain : | A, B, C, D | ||||||||
---|---|---|---|---|---|---|---|---|---|
UniProt : | P22411 (DPP4_PIG) | ||||||||
|