Brand  (β version)

color scheme of protein:

hetatm:

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information
centroid:
interaction residue:

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Ligands
Code Name Link
ACT Acetate ion
FON N-{[4-({[(6r)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]carbonyl}-L-glutamic acid
U5P Uridine-5'-monophosphate
Code : 2BLN
Header : TRANSFERASE
Title : N-terminal formyltransferase domain of ArnA in complex with N-5- formyltetrahydrofolate and UMP
Release Data : 2005-04-08
Compound :
mol_id molecule chains synonym
1 PROTEIN YFBG A,B UDP-D-GLUCURONATE DEHYDROGENASE ARNA
ec: 2.1.1.2
fragment: FORMYLTRANSFERASE DOMAIN, RESIDUES 1-305
Source :
mol_id organism_scientific expression_system
1 ESCHERICHIA COLI  (taxid:562) ESCHERICHIA COLI  (taxid:469008)
strain: W3310
expression_system_strain: BL21(DE3)
expression_system_plasmid: PET24B
Authors : Williams, G.J., Breazeale, S.D., Raetz, C.R.H., Naismith, J.H.
Keywords : TRANSFERASE, FORMYLTRANSFERASE, L-ARA4N BIOSYNTHESIS, METHYLTRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 1.20 Å )
Citation :

Structure and Function of Both Domains of Arna, a Dual Function Decarboxylase and a Formyltransferase, Involved in 4-Amino-4-Deoxy-L-Arabinose Biosynthesis.

Williams, G.J.,Breazeale, S.D.,Raetz, C.R.H.  et al.
(2005)  J.Biol.Chem.  280 : 23000

PubMed: 15809294
DOI: 10.1074/JBC.M501534200

Chain : A, B
UniProt : P77398 (ARNA_ECOLI)
Reaction : UDP-alpha-D-glucuronate + NAD(+) = UDP-beta-L- threo-pentapyranos-4-ulose + CO(2) + NADH.
10-formyltetrahydrofolate + UDP-4-amino-4- deoxy-beta-L-arabinose = 5,6,7,8-tetrahydrofolate + UDP-4-deoxy-4- formamido-beta-L-arabinose.