PDB ID: 2BL9
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Structure summary
Code : | 2BL9 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | OXIDOREDUCTASE | ||||||||||||
Title : | X-ray crystal structure of Plasmodium vivax dihydrofolate reductase in complex with pyrimethamine and its derivative | ||||||||||||
Release Data : | 2005-09-07 | ||||||||||||
Compound : |
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Source : |
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Authors : | Kongsaeree, P., Khongsuk, P., Leartsakulpanich, U., Chitnumsub, P., Tarnchompoo, B., Walkinshaw, M.D., Yuthavong, Y. | ||||||||||||
Keywords : | DIHYDROFOLATE REDUCTASE, PLAMODIUM VIVAX, PYRIMETHAMINE, MALARIA, DRUG RESISTANCE, OXIDOREDUCTASE | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.90 Å ) | ||||||||||||
Citation : |
Crystal Structure of Dihydrofolate Reductase from Plasmodium Vivax: Pyrimethamine Displacement Linked with Mutation-Induced Resistance.
Kongsaeree, P.,Khongsuk, P.,Leartsakulpanich, U.
et al.
PubMed: 16135570 |
Reaction
Chain : | A |
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UniProt : | Q9U0E8 (Q9U0E8_PLAVI) |
Reaction : | - |