Het-PDB Navi2 (PDB: 2BJ4)

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Ligands
Code	Name		Style	Show	Link
OHT	4-hydroxytamoxifen				PoSSuM

Non-standard Residues
Code	Name	Show
CCS	Carboxymethylated cysteine

Glycosylation
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Modification
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Download interaction data: 2BJ4

Code :

2BJ4 PDBj RCSB PDB PDBe

Header :

NUCLEAR RECEPTOR

Title :

ESTROGEN RECEPTOR ALPHA LBD IN COMPLEX WITH A PHAGE-DISPLAY DERIVED PEPTIDE ANTAGONIST

Release Data :

2005-02-16

Compound :

mol_id	molecule	chains	synonym
1	ESTROGEN RECEPTOR	A	ER, ESTRADIOL RECEPTOR, ER-ALPHA
	fragment: RESIDUES 305-533 (LIGAND-BINDING DOMAIN)

mol_id	molecule	chains	synonym
2	ESTROGEN RECEPTOR	B	ER, ESTRADIOL RECEPTOR, ER-ALPHA
	fragment: RESIDUES 305-533 (LIGAND-BINDING DOMAIN)

mol_id	molecule	chains
3	PEPTIDE ANTAGONIST	C,D

Source :

mol_id	organism_scientific	organism_common	expression_system
1	HOMO SAPIENS (taxid:9606)	HUMAN	ESCHERICHIA COLI BL21(DE3) (taxid:469008)
	expression_system_variant: C41 expression_system_plasmid: PET15B

mol_id	organism_scientific	organism_common	expression_system
2	HOMO SAPIENS (taxid:9606)	HUMAN	ESCHERICHIA COLI BL21(DE3) (taxid:469008)
	expression_system_variant: C41 expression_system_plasmid: PET15B

mol_id	organism_scientific
3	SYNTHETIC CONSTRUCT (taxid:32630)
	synthetic: yes

Authors :

Kong, E., Heldring, N., Gustafsson, J.A., Treuter, E., Hubbard, R.E., Pike, A.C.W.

Keywords :

NUCLEAR RECEPTOR, TRANSCRIPTION FACTOR, PEPTIDE ANTAGONIST, LIGAND-BINDING DOMAIN (LBD), DNA-BINDING, NUCLEAR PROTEIN STEROID-BINDING

Exp. method :

X-RAY DIFFRACTION ( 2.00 Å )

Citation :

Delineation of a Unique Protein-Protein Interaction Site on the Surface of the Estrogen Receptor

Kong, E.,Heldring, N.,Gustafsson, J.A. et al.
(2005) Proc.Natl.Acad.Sci.USA 102 : 3593

PDB ID: 2BJ4