Brand  (β version)

PDB ID: 2B76

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Ligands
Code Name Style Show Link
FLC Citrate anion PoSSuM
FAD Flavin-adenine dinucleotide PoSSuM
FES Fe2/s2 (inorganic) cluster PoSSuM
F3S Fe3-s4 cluster PoSSuM
SF4 Iron/sulfur cluster PoSSuM
MQ7 Menaquinone-7 PoSSuM
Non-standard Residues
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Structure summary

Code : 2B76   PDBj   RCSB PDB   PDBe
Header : OXIDOREDUCTASE
Title : E. coli Quinol fumarate reductase FrdA E49Q mutation
Release Data : 2006-02-21
Compound :
mol_id molecule chains
1 Fumarate reductase flavoprotein subunit A,M
mutation: E49Q
mol_id molecule chains
2 Fumarate reductase iron-sulfur protein B,N
ec: 1.3.99.1
mol_id molecule chains synonym
3 Fumarate reductase subunit C C,O Fumarate reductase 15 kDa hydrophobic protein
mol_id molecule chains synonym
4 Fumarate reductase subunit D D,P Fumarate reductase 13 kDa hydrophobic protein
Source :
mol_id organism_scientific expression_system
1 Escherichia coli  (taxid:562) Escherichia coli  (taxid:562)
gene: FrdA
expression_system_strain: DW35
expression_system_vector_type: PLASMID
expression_system_plasmid: PH3
mol_id organism_scientific expression_system
2 Escherichia coli  (taxid:562) Escherichia coli  (taxid:562)
gene: frdB
expression_system_strain: DW35
expression_system_vector_type: PLASMID
expression_system_plasmid: PH3
mol_id organism_scientific expression_system
3 Escherichia coli  (taxid:562) Escherichia coli  (taxid:562)
gene: frdC
expression_system_strain: DW35
expression_system_vector_type: PLASMID
expression_system_plasmid: PH3
mol_id organism_scientific expression_system
4 Escherichia coli  (taxid:562) Escherichia coli  (taxid:562)
gene: frdD
expression_system_strain: DW35
expression_system_vector_type: PLASMID
expression_system_plasmid: PH3
Authors : Maklashina, E., Iverson, T.M., Sher, Y., Kotlyar, V., Mirza, O., Andrell, J., Hudson, J.M., Armstrong, F.A., Cecchini, G.
Keywords : fumarate reductase, succinate dehydrogenase, electron transfer, respiration, krebs cycle, membrane protein, OXIDOREDUCTASE
Exp. method : X-RAY DIFFRACTION ( 3.300 Å )
Citation :

Fumarate Reductase and Succinate Oxidase Activity of Escherichia coli Complex II Homologs Are Perturbed Differently by Mutation of the Flavin Binding Domain

Maklashina, E.,Iverson, T.M.,Sher, Y.  et al.
(2006)  J.Biol.Chem.  281 : 11357 - 11365

PubMed: 16484232
DOI: 10.1074/jbc.M512544200

Reaction

Chain : B, N
UniProt : P00364 (multiple entry names are found)
Reaction : -
Chain : C, O
UniProt : P0A8Q0 (FRDC_ECOLI)
Reaction : -
Chain : D, P
UniProt : P0A8Q3 (FRDD_ECOLI)
Reaction : -