Brand  (β version)

PDB ID: 2AY7

Hetero Atom Contents

  The number of atoms exceeds 100,000.
  So, it can not be displayed here.

Select unit:

Select hetatm:   

close
information
centroid:
interaction residue:

Select chain:   Sequence  

Data format:   

Color scheme of protein:

Ligands
Code Name Style Show Link
CLT 4-phenyl-butanoic acid PoSSuM
PLP Pyridoxal-5'-phosphate PoSSuM
Non-standard Residues
Code Name Show
Glycosylation
Code Name Emphasize
Modification
Code Name Show

Structure summary

Code : 2AY7   PDBj   RCSB PDB   PDBe
Header : AMINOTRANSFERASE
Title : AROMATIC AMINO ACID AMINOTRANSFERASE WITH 4-PHENYLBUTYRIC ACID
Release Data : 1999-02-02
Compound :
mol_id molecule chains synonym
1 AROMATIC AMINO ACID AMINOTRANSFERASE A,B AROAT
ec: 2.6.1.57
Source :
mol_id organism_scientific expression_system
1 Paracoccus denitrificans  (taxid:266) Escherichia coli  (taxid:562)
strain: IFO12442
expression_system_strain: TY103
expression_system_plasmid: PUC118
Authors : Okamoto, A., Hirotsu, K., Kagamiyama, H.
Keywords : AMINOTRANSFERASE, AROMATIC AMINO ACID BIOSYNTHESIS
Exp. method : X-RAY DIFFRACTION ( 2.40 Å )
Citation :

The active site of Paracoccus denitrificans aromatic amino acid aminotransferase has contrary properties: flexibility and rigidity.

Okamoto, A.,Ishii, S.,Hirotsu, K.  et al.
(1999)  Biochemistry  38 : 1176 - 1184

PubMed: 9930977
DOI: 10.1021/bi981921d

Crystal Structures of Paracoccus Denitrificans Aromatic Amino Acid Aminotransferase: A Substrate Recognition Site Constructed by Rearrangement of Hydrogen Bond Network

Okamoto, A.,Nakai, Y.,Hayashi, H.  et al.
(1998)  J.Mol.Biol.  280 : 443

Paracoccus Denitrificans Aromatic Amino Acid Aminotransferase: A Model Enzyme for the Study of Dual Substrate Recognition Mechanism

Oue, S.,Okamoto, A.,Nakai, Y.  et al.
(1997)  J.Biochem.(Tokyo)  121 : 161

Reaction

Chain : A, B
UniProt : P95468 (TYRB_PARDE)
Reaction: EC: Evidence:
Physiological Direction:
2-oxoglutarate + an aromatic L-alpha-amino acid = an aromatic oxo-acid + L-glutamate 2.6.1.57 -
-