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Ligands
Code Name Style Show Link
FHM S-3-(4-fluorophenoxy)-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide
Non-standard Residues
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Glycosylation
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Modification
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Code : 2AX8   PDBj   RCSB PDB   PDBe
Header : TRANSCRIPTION
Title : Crystal Structure Of The Androgen Receptor Ligand Binding Domain W741L Mutant In Complex With S-1
Release Data : 2005-09-20
Compound :
mol_id molecule chains
1 Androgen receptor A
fragment: Ligand Binding Domain (residues 663-918)
mutation: W741L
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli BL21(DE3)  (taxid:469008)
gene: Ar
expression_system_strain: BL21DE3
expression_system_vector_type: Plasmid
expression_system_plasmid: pGEX6P-1
Authors : Bohl, C.E., Miller, D.D., Chen, J., Bell, C.E., Dalton, J.T.
Keywords : TRANSCRIPTION
Exp. method : X-RAY DIFFRACTION ( 1.70 Å )
Citation :

Structural Basis for Accommodation of Nonsteroidal Ligands in the Androgen Receptor

Bohl, C.E.,Miller, D.D.,Chen, J.  et al.
(2005)  J.Biol.Chem.  280 : 37747 - 37754

PubMed: 16129672
DOI: 10.1074/jbc.M507464200

Chain : A
UniProt : P10275 (ANDR_HUMAN)
Reaction : -