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Ligands
Code Name Style Show Link
CL Chloride ion
F Fluoride ion
MN Manganese (II) ion
NA Sodium ion
PO4 Phosphate ion
POP Pyrophosphate 2-
Non-standard Residues
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Glycosylation
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Code : 2AU6   PDBj   RCSB PDB   PDBe
Header : HYDROLASE
Title : Crystal structure of catalytic intermediate of inorganic pyrophosphatase
Release Data : 2006-08-29
Compound :
mol_id molecule chains synonym
1 Inorganic pyrophosphatase A Pyrophosphate phospho- hydrolase, PPase
ec: 3.6.1.1
Source :
mol_id organism_scientific expression_system
1 Escherichia coli  (taxid:562) Escherichia coli  (taxid:562)
expression_system_strain: JM109
expression_system_vector_type: PLASMID
expression_system_plasmid: PUC19
Authors : Samygina, V.R., Popov, A.N., Avaeva, S.M., Bartunik, H.D.
Keywords : hydrolase, intermediate, inorganic pyrophosphatase
Exp. method : X-RAY DIFFRACTION ( 1.20 Å )
Citation :

Reversible inhibition of Escherichia coli inorganic pyrophosphatase by fluoride: trapped catalytic intermediates in cryo-crystallographic studies

Samygina, V.R.,Moiseev, V.M.,Rodina, E.V.  et al.
(2007)  J.Mol.Biol.  366 : 1305 - 1317

PubMed: 17196979
DOI: 10.1016/j.jmb.2006.11.082

Chain : A
UniProt : P0A7A9 (IPYR_ECOLI)
Reaction: EC: Evidence:
Physiological Direction:
diphosphate + H2O = H(+) + 2 phosphate 3.6.1.1 HAMAP- Rule:MF_00209
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