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Ligands
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JE2 (4r)-3-{(2s,3s)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-phenylbutanoyl}-5,5-dimethyl-N-(2-methylbenzyl)-1,3-thiazolidine-4-carboxamide
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Code : 2ANL   PDBj   RCSB PDB   PDBe
Header : HYDROLASE/HYDROLASE INHIBITOR
Title : X-ray crystal structure of the aspartic protease plasmepsin 4 from the malarial parasite plasmodium malariae bound to an allophenylnorstatine based inhibitor
Release Data : 2006-04-04
Compound :
mol_id molecule chains
1 plasmepsin IV A,B
Source :
mol_id organism_scientific expression_system
1 Plasmodium malariae  (taxid:5858) Escherichia coli  (taxid:562)
Authors : Clemente, J.C., Govindasamy, L., Madabushi, A., Fisher, S.Z., Moose, R.E., Yowell, C.A., Hidaka, K., Kimura, T., Hayashi, Y., Kiso, Y., Agbandje-McKenna, M., Dame, J.B., Dunn, B.M., McKenna, R.
Keywords : Plasmodium parasite, plasmepsin 4, aspartic protease, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR complex
Exp. method : X-RAY DIFFRACTION ( 3.3 Å )
Citation :

Structure of the aspartic protease plasmepsin 4 from the malarial parasite Plasmodium malariae bound to an allophenylnorstatine-based inhibitor.

Clemente, J.C.,Govindasamy, L.,Madabushi, A.  et al.
(2006)  Acta Crystallogr.,Sect.D  62 : 246 - 252

PubMed: 16510971
DOI: 10.1107/S0907444905041260

Chain : A, B
UniProt : O60990 (O60990_PLAMA)
Reaction : -