Brand  (β version)

PDB ID: 2AIG

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Ligands
Code Name Style Show Link
0GR N-(furan-2-ylcarbonyl)-L-leucyl-L-tryptophan PoSSuM
ZN Zinc ion PoSSuM
CA Calcium ion PoSSuM
SO4 Sulfate ion PoSSuM
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Structure summary

Code : 2AIG   PDBj   RCSB PDB   PDBe
Header : HYDROLAST/HYDROLASE INHIBITOR
Title : ADAMALYSIN II WITH PEPTIDOMIMETIC INHIBITOR POL647
Release Data : 1998-04-15
Compound :
mol_id molecule chains
1 ADAMALYSIN II P
ec: 3.4.24.46
Source :
mol_id organism_scientific organism_common
1 Crotalus adamanteus  (taxid:8729) Eastern diamondback rattlesnake
tissue: VENOM
secretion: VENOM
Authors : Gomis-Rueth, F.X., Meyer, E.F., Kress, L.F., Politi, V.
Keywords : ZINC PROTEASE, METALLOENDOPETIDASE, COMPLEX OF METALLOPROTEASE-INHIBITOR, HYDROLAST-HYDROLASE INHIBITOR COMPLEX
Exp. method : X-RAY DIFFRACTION ( 2.6 Å )
Citation :

Structures of adamalysin II with peptidic inhibitors. Implications for the design of tumor necrosis factor alpha convertase inhibitors.

Gomis-Ruth, F.X.,Meyer, E.F.,Kress, L.F.  et al.
(1998)  Protein Sci.  7 : 283 - 292

PubMed: 9521103

Refined 2.0 A X-Ray Crystal Structure of the Snake Venom Zinc-Endopeptidase Adamalysin II. Primary and Tertiary Structure Determination, Refinement, Molecular Structure and Comparison with Astacin, Collagenase and Thermolysin

Gomis-Ruth, F.X.,Kress, L.F.,Kellermann, J.  et al.
(1994)  J.Mol.Biol.  239 : 513

First Structure of a Snake Venom Metalloproteinase: A Prototype for Matrix Metalloproteinases/Collagenases

Gomis-Ruth, F.X.,Kress, L.F.,Bode, W.
(1993)  Embo J.  12 : 4151