Brand  (β version)

PDB ID: 2A9C

Hetero Atom Contents

  The number of atoms exceeds 100,000.
  So, it can not be displayed here.

Select unit:

Select hetatm:   

close
information
centroid:
interaction residue:

Select chain:   Sequence  

Data format:   

Color scheme of protein:

Ligands
Code Name Style Show Link
GOL Glycerol PoSSuM
MO Molybdenum atom PoSSuM
MTE Phosphonic acidmono-(2-amino-5,6-dimercapto-4-oxo-3,7,8a,9,10,10a-hexahydro-4h-8-oxa-1,3,9,10-tetraaza-anthracen-7-ylmethyl)ester PoSSuM
SO4 Sulfate ion PoSSuM
Non-standard Residues
Code Name Show
Glycosylation
Code Name Emphasize
Modification
Code Name Show

Structure summary

Code : 2A9C   PDBj   RCSB PDB   PDBe
Header : OXIDOREDUCTASE
Title : Crystal structure of R138Q mutant of recombinant chicken sulfite oxidase with the bound product, sulfate, at the active site
Release Data : 2005-08-02
Compound :
mol_id molecule chains
1 Sulfite Oxidase A,B
ec: 1.8.3.1
fragment: Catalytic core domain and C terminal dimerization domain
mutation: R138Q
Source :
mol_id organism_scientific organism_common expression_system
1 Gallus gallus  (taxid:9031) Chicken Escherichia coli  (taxid:562)
organ: Liver
organelle: Mitochondrion
cellular_location: Mitochondrial Intermembrane Space
gene: SUOX
expression_system_strain: TP1000
expression_system_vector_type: plasmid
expression_system_plasmid: pTrc99A
other_details: The gene is chemically synthesized based on the protein sequence of sulfite oxidase from Gallus gallus
Authors : Karakas, E., Wilson, H.L., Graf, T.N., Xiang, S., Jaramillo-Busquets, S., Rajagopalan, K.V., Kisker, C.
Keywords : sulfite oxidase; Molybdopterin; Molybdenum; CSO; sulfate; R138Q; R160Q, OXIDOREDUCTASE
Exp. method : X-RAY DIFFRACTION ( 2.505 Å )
Citation :

Structural insights into sulfite oxidase deficiency

Karakas, E.,Wilson, H.L.,Graf, T.N.  et al.
(2005)  J.Biol.Chem.  280 : 33506 - 33515

PubMed: 16048997
DOI: 10.1074/jbc.M505035200

Reaction

Chain : A, B
UniProt : P07850 (SUOX_CHICK)
Reaction: EC: Evidence:
Physiological Direction:
sulfite + O2 + H2O = sulfate + H2O2 1.8.3.1 PubMed:2687265
left-to-right
Cofactor: Evidence: Note:
heme b ECO:0000269 | PubMed:9428520
Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
Mo-molybdopterin ECO:0000269 | PubMed:9428520
Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.