Brand  (β version)

color scheme of protein:

hetatm:
centroid:

chain: Hide other chain(s)

Ligands
Code Name Link
HT 2'-(4-hydroxyphenyl)-5-(4-methyl-1-piperazinyl)-2,5'-bi-benzimidazole
Code : 264D
Header : DNA
Title : THREE-DIMENSIONAL CRYSTAL STRUCTURE OF THE A-TRACT DNA DODECAMER D(CGCAAATTTGCG) COMPLEXED WITH THE MINOR-GROOVE-BINDING DRUG HOECHST 33258
Release Data : 1995-03-31
Compound :
mol_id molecule chains
1 DNA (5'-D(*CP*GP*CP*AP*AP*AP*TP*TP*TP*GP*CP*G)-3') A,B
Source :
mol_id organism_scientific
1
synthetic: yes
Authors : Vega, M.C., Garcia-Saez, I., Aymami, J., Eritja, R., Van Der Marel, G.A., Van Boom, J.H., Rich, A., Coll, M.
Keywords : B-DNA, DOUBLE HELIX, COMPLEXED WITH DRUG, DNA
Exp. method : X-RAY DIFFRACTION ( 2.440 Å )
Citation :

Three-dimensional crystal structure of the A-tract DNA dodecamer d(CGCAAATTTGCG) complexed with the minor-groove-binding drug Hoechst 33258.

Vega, M.C.,Garcia Saez, I.,Aymami, J.  et al.
(1994)  Eur.J.Biochem.  222 : 721 - 726

PubMed: 7517864
DOI: 10.1111/j.1432-1033.1994.tb18917.x

Binding of a Hoechst dye to d(CGCGATATCGCG) and its influence on the conformation of the DNA fragment.

Carrondo, M.A.,Coll, M.,Aymami, J.  et al.
(1989)  Biochemistry  28 : 7849 - 7859

PubMed: 2482071

A Bifurcated Hydrogen-Bonded Conformation in the d(A.T) Base Pairs of the DNA Dodecamer d(CGCAAATTTGCG) and Its Complex with Distamycin

Coll, M.,Frederick, C.A.,Wang, A.H.-J.  et al.
(1987)  Proc.Natl.Acad.Sci.USA  84 : 8385 - 8389