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Ligands
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CMD 3'-desamino-3'-(3-cyano-4-morpholinyl)-doxorubicin
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Code : 236D   PDBj   RCSB PDB   PDBe
Header : DNA
Title : CRYSTAL STRUCTURE OF FOUR MORPHOLINO-DOXORUBICIN ANTICANCER DRUGS COMPLEXED WITH D(CGTACG) AND D(CGATCG): IMPLICATIONS IN DRUG-DNA CROSSLINK
Release Data : 1996-01-31
Compound :
mol_id molecule chains
1 DNA (5'-D(*CP*GP*AP*TP*CP*G)-3') A
Source :
mol_id organism_scientific
1
synthetic: yes
Authors : Gao, Y.-G., Wang, A.H.-J.
Keywords : RIGHT HANDED DNA, DOUBLE HELIX, COMPLEXED WITH DRUG, DNA
Exp. method : X-RAY DIFFRACTION ( 1.800 Å )
Citation :

Crystal structures of four morpholino-doxorubicin anticancer drugs complexed with d(CGTACG) and d(CGATCG): implications in drug-DNA crosslink.

Gao, Y.G.,Wang, A.H.
(1995)  J.Biomol.Struct.Dyn.  13 : 103 - 117

PubMed: 8527023