PDB ID: 1ZPB
Hetero Atom Contents
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Code | Name | Style | Show | Link | |
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995 | 4-methyl-pentanoic acid {1-[4-guanidino-1-(thiazole-2-carbonyl)-butylcarbamoyl]-2-methyl-propyl}-amide | PoSSuM | |||
SO4 | Sulfate ion | PoSSuM |
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Download interaction data: 1ZPB
Structure summary
Code : | 1ZPB PDBj RCSB PDB PDBe | ||||||||||||
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Header : | HYDROLASE | ||||||||||||
Title : | Crystal Structure of the Catalytic Domain of Coagulation Factor XI in Complex with 4-Methyl-pentanoic acid {1-[4-guanidino-1-(thiazole-2-carbonyl)-butylcarbamoyl]-2-methyl-propyl}-amide | ||||||||||||
Release Data : | 2006-04-18 | ||||||||||||
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Authors : | Deng, H., Bannister, T.D., Jin, L., Nagafuji, P., Celatka, C.A., Lin, J., Lazarova, T.I., Rynkiewicz, M.J., Quinn, J., Bibbins, F., Pandey, P., Gorga, J., Babine, R.E., Meyers, H.V., Abdel-Meguid, S.S., Strickler, J.E. | ||||||||||||
Keywords : | FXI, Inhibitor, HYDROLASE | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.10 Å ) | ||||||||||||
Citation : |
Synthesis, SAR exploration, and X-ray crystal structures of factor XIa inhibitors containing an alpha-ketothiazole arginine
Deng, H.,Bannister, T.D.,Jin, L.
et al.
PubMed: 16524727 |
Reaction
Chain : | A | ||||||||
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UniProt : | P03951 (FA11_HUMAN) | ||||||||
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