PDB ID: 1ZEO
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Structure summary
Code : | 1ZEO PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSCRIPTION | ||||||||||||
Title : | Crystal Structure of Human PPAR-gamma Ligand Binding Domain Complexed with an Alpha-Aryloxyphenylacetic Acid Agonist | ||||||||||||
Release Data : | 2006-04-25 | ||||||||||||
Compound : |
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Source : |
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Authors : | Shi, G.Q., Dropinski, J.F., McKeever, B.M., Adams, A.D., MacNaul, K.L., Elbrecht, A., Berger, J.P., Zhou, G., Doebber, T.W. | ||||||||||||
Keywords : | Nuclear receptor, Ligand Binding Domain, LBD, Alpha helix sandwich, PPAR-RXR heterodimer, TRANSCRIPTION | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.50 Å ) | ||||||||||||
Citation : |
Design and Synthesis of alpha-Aryloxyphenylacetic Acid Derivatives: A Novel Class of PPAR alpha/gamma Dual Agonists with Potent Antihyperglycemic and Lipid Modulating Activity
Shi, G.Q.,Dropinski, J.F.,McKeever, B.M.
et al.
PubMed: 15974597 |
Reaction
Chain : | A, B |
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UniProt : | P37231 (PPARG_HUMAN) |
Reaction : | - |