Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
CO Cobalt (II) ion
EL Ellipticine
Code : 1Z3F
Header : DNA
Title : Structure of ellipticine in complex with a 6-bp DNA
Release Data : 2005-07-19
Compound :
mol_id molecule chains
1 5'-D(*CP*GP*AP*TP*CP*G)-3' A,B
Source :
mol_id organism_scientific
1
synthetic: yes
Authors : Canals, A., Purciolas, M., Aymami, J., Coll, M.
Keywords : ANTICANCER, DNA BINDING, DRUG DESIGN, ELLIPTICINE, INTERCALATOR, DNA
Exp. method : X-RAY DIFFRACTION ( 1.50 Å )
Citation :

The anticancer agent ellipticine unwinds DNA by intercalative binding in an orientation parallel to base pairs.

Canals, A.,Purciolas, M.,Aymami, J.  et al.
(2005)  Acta Crystallogr.,Sect.D  61 : 1009 - 1012

PubMed: 15983425
DOI: 10.1107/S0907444905015404