Brand  (β version)

  The number of atoms exceeds 100,000.
  So, it can not be displayed here.

Select unit:

Select hetatm:   

close
information
centroid:
interaction residue:

Select chain:   Sequence  

Data format:   

Color scheme of protein:

Ligands
Code Name Style Show Link
DMA Dimethylallyl diphosphate
MG Magnesium ion
RIS 1-hydroxy-2-(3-pyridinyl)ethylidene bis-phosphonic acid
SO4 Sulfate ion
Non-standard Residues
Code Name Show
Glycosylation
Code Name Emphasize
Modification
Code Name Show
Code : 1YHL   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : Structure of the complex of Trypanosoma cruzi farnesyl diphosphate synthase with risedronate, dmapp and Mg+2
Release Data : 2005-12-20
Compound :
mol_id molecule chains
1 farnesyl pyrophosphate synthase A
Source :
mol_id organism_scientific expression_system
1 Trypanosoma cruzi  (taxid:5693) Escherichia coli BL21  (taxid:511693)
expression_system_strain: BL21
expression_system_vector_type: pet28
Authors : Gabelli, S.B., McLellan, J.S., Montalvetti, A., Oldfield, E., Docampo, R., Amzel, L.M.
Keywords : farnesyl diphosphate synthase, bisphosphonate, dimethyl allyl pyrophosphate sulfate, FPPS, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 1.95 Å )
Citation :

Structure and mechanism of the farnesyl diphosphate synthase from Trypanosoma cruzi: Implications for drug design.

Gabelli, S.B.,McLellan, J.S.,Montalvetti, A.  et al.
(2005)  Proteins  62 : 80 - 88

PubMed: 16288456
DOI: 10.1002/prot.20754

Chain : A
UniProt : Q8WS26 (Q8WS26_TRYCR)
Reaction : -